Long-Acting Injectable Antipsychotics in First-Episode Schizophrenia
نویسندگان
چکیده
1Clinic Schizophrenia Program (PEC), Department of Psychiatry, Hospital Clinic of Barcelona, University of Barcelona, 08036 Barcelona, Catalonia, Spain 2Department of Psychiatry, University of Texas Health Science Center San Antonio, 7300 Floyd Curl Drive, San Antonio, TX 78229, USA 3Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town 7500, South Africa 4Klinik und Poliklinic für Psychiatrie und Psychotherapie, Klinikum Rechts der Isar, Technische Universitaet München, Moehlstraße 26, 81675 München, Germany
منابع مشابه
Long-Acting Injectable Antipsychotics for First-Episode Schizophrenia: The Pros and Cons
Clinical and psychosocial deterioration associated with schizophrenia occurs within the first few years following the onset of the illness. Therefore, to improve the long-term prognosis, it is important to provide schizophrenia patients with intensive treatment following their first episode. Relapse is highly associated with partial medication adherence or nonadherence in patients with first-ep...
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Antipsychotic medications are important for the successful management of schizophrenia. Continuous treatment with medication is superior in relapse prevention and non-adherence to antipsychotic medication is associated with a poor clinical outcome. Long-acting injectable antipsychotics (LAIs) that can guarantee adherence to a treatment regimen could be a useful treatment option. With the introd...
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Long-acting injectable antipsychotics (LAIs) should offer better efficacy and tolerability, compared to oral antipsychotics due to improved adherence and more stable pharmacokinetics. However, data on LAIs has been mixed, with some studies finding that they are more effective and tolerable than oral antipsychotics, and others finding the contrary. One possibility for the disparate results may b...
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AIM Results from clinical trials support the use of oral antipsychotics for treatment of early or first-episode psychosis in patients with schizophrenia. This paper will review literature on the advantages of early initiation of treatment for schizophrenia and the clinical benefits of early use of long-acting injectable antipsychotics (LAIs). METHOD A comprehensive literature review was condu...
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ورودعنوان ژورنال:
دوره 2012 شماره
صفحات -
تاریخ انتشار 2012